Pain Med. 2012 Jan 5. doi: 10.1111/j.1526-4637.2011.01304.x. [Epub ahead =
of print]
Vitamin D Deficiency in Women with Fibromyalgia in Saudi Arabia.
Abokrysha NT.
Source
Department of Neurology, Cairo University, Kaser Al-Aini Hospital, Al-Man=
yal, Cairo, Egypt Bugshan Hospital, Jeddah, Kingdom of Saudi Arabia.
Abstract
Background.=E2=80=82 The relation between low levels of 25-hydroxyvitamin=
D and nonspecific musculoskeletal pain, including fibromyalgia syndrome,=
is debatable. Many studies have reported "a positive relation" and other=
s "found no relation." Objectives.=E2=80=82 To determine the prevalence o=
f vitamin D deficiency among patients with fibromyalgia in a neurology cl=
inic in the Kingdom of Saudi Arabia (KSA). Methods.=E2=80=82 This study w=
as done at a neurology clinic of Bugshan Hospital, Jeddah, KSA, from Janu=
ary to April 2011. Thirty female patients were diagnosed with fibromyalgi=
a according to new clinical fibromyalgia diagnostic criteria; their serum=
vitamin D levels were screened. Vitamin D deficiency is defined as <20=E2=
=80=83ng/mL, vitamin D insufficiency is defined as 21-29=E2=80=83ng/mL, a=
nd vitamin D sufficiency is equal to or >30=E2=80=83ng/mL. Result.=E2=80=82=
Thirty female patients were included in the study. The mean age was 34.5=
6=E2=80=83=C2=B1=E2=80=838.1=E2=80=83years. Mean vitamin D level was 4.76=
=E2=80=83=C2=B1=E2=80=831.46=E2=80=83ng/mL. A significant negative correl=
ation between vitamin D level and widespread pain index was found. Thirty=
percent of the patients were Saudi Arabian of whom 100% were veiled; 70%=
were non-Saudi Arabian of whom 47.6% were veiled and 52.4% wore long pan=
ts and/or full sleeved clothes. Vitamin D deficiency was equally prevalen=
t among veiled (4.77=E2=80=83=C2=B1=E2=80=831.37=E2=80=83ng/mL) and nonve=
iled (4.75=E2=80=83=C2=B1=E2=80=831.68=E2=80=83ng/mL). Treatment with hig=
h-dose vitamin D resulted in clinical improvement in all patients. Conclu=
sion.=E2=80=82 Vitamin D deficiency is often seen in patients diagnosed w=
ith fibromyalgia in our population. This was equally true in veiled and n=
onveiled, but conservatively dressed populations. Effective treatment wit=
h high-dose vitamin D could lead to resolution of almost all symptoms. Fu=
rther study of these populations and fortification of foods with vitamin =
D may be essential.
Wiley Periodicals, Inc.
PMID:=20
22221390=20
[PubMed - as supplied by publisher]=20
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