J Int Med Res. 2011;39(1):212-4.
Increased tenderness in the left third intercostal space in adult
patients with myalgic encephalomyelitis: a controlled study.
Puri BK, Gunatilake KD, Fernando KA, Gurusinghe AI, Agour M, Treasaden IH.
SourceImaging Department, Hammersmith Hospital, Du Cane Road, London
W12 0HS, UK. basant.puri@imperial.ac.uk
Abstract
A clinical sign has not thus far been associated with myalgic
encephalo myelitis (ME). The present study involved systematic
clinical examination that included inspection, palpation, percussion
and auscultation of the thorax of 42 ME patients and 20 age-matched
healthy controls while sitting. Left lateral third intercostal space
tenderness was noted in 34 (81%) of the patients and in none of the
controls, a difference that was highly statistically significant. This
finding may be related to changes in lymphatic function and to the
descending course of the thoracic duct. Further studies, preferably
blinded and combined with appropriate imaging, are required.
PMID:21672323[PubMed - indexed for MEDLINE]
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