Disease Control has been pressed for by advocates, public watchdogs
and scientists alike in many areas of government. http://www.data.gov/
The CDC RP has now made the datasets involved in the Wichita Clinical
Study available. Gene Expression data is also available to scientists
by request. Email rdca@cdc.gov with the subject "Wichita CFS Gene
Expression Data."
Wichita Clinical Study Data Access
The data sets were collected during a 2-day in-hospital clinical
assessment study conducted from December 2002 to July 2003 in Wichita,
KS, USA (referred to as Wichita Clinical Study). The study enrolled
227 people and classified them into study groups. Each group was based
on particular criteria, including those who:
Meet the 1994 CFS international case definition (CFS)
Meet the 1994 CFS international case definition except that a major
depressive disorder with melancholic features was identified
(CFS-MDDm)
Are chronically fatigued but not meeting the CFS case definition
because of insufficient number of symptoms or fatigue severity (ISF)
Are chronically fatigued but with ISF and a major depressive disorder
with melancholic features (ISF-MDDm)
Are non-fatigued controls matched to CFS subjects on age,
race/ethnicity, sex, and body mass index (NF)
Assessment included clinical evaluation of each subject's medical and
psychiatric status, sleep characteristics and cognitive functioning.
Laboratory testing evaluated neuroendocrine status, autonomic nervous
system function, systemic cytokine profiles, peripheral blood gene
expression patterns and polymorphisms in genes involved in
neurotransmission and immune regulation. Evaluation was performed
without knowledge of disease classification.
Further details about this study are provided in the study overview
document (found below), which should be read before using any data
set. The documents associated with each data set contain the
information necessary for understanding the included variables. This
web site contains documents only.
CDC Chronic Viral Diseases Branch is making the data accessible to
researchers through CDC's NCHS Research Data Center (RDC). All
researchers and users interested in the data shall be subject to all
RDC procedures and protocols. Instructions on how access the data sets
are available on the RDC Web site.
http://www.cdc.gov/cfs/programs/wichita-data-access/index.html
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