Wednesday, December 16, 2009

res: New Pediatric Case Definition ME/CFS -Severe versus Moderate Criteria

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PubMed

Child Psychiatry Hum Dev. 2009 Dec;40(4):609-20.
Epub 2009 Jun 10.


Severe versus Moderate
criteria for the new pediatric
case definition for ME/CFS.

Jason L, Porter N, Shelleby E, Till L,
Bell DS, Lapp CW, Rowe K, De Meirleir K.

Center for Community Research, DePaul
University, Chicago, IL 60614, USA.
Ljason@depaul.edu


The new diagnostic criteria for pediatric ME/CFS are
structurally based on the Canadian Clinical Adult
case definition, and have more required specific
symptoms than the (Fukuda et al. Ann Intern Med
121:953-959, 1994) adult case definition.


Physicians specializing in pediatric ME/CFS referred
thirty-three pediatric patients with ME/CFS and 21
youth without the illness.

Those who met ME/CFS criteria were separated into
Severe and Moderate categories.

Significant differences were found for symptoms
within each of the six major categories: fatigue,
post-exertional malaise, sleep, pain, neurocognitive
difficulties, and autonomic/neuroendocrine/immune
manifestations.

In general, the results showed participants who met
the Severe ME/CFS criteria reported the highest
scores, the Moderate ME/CFS group show scores that
were a little lower, and the control group evidenced
the lowest scores.

Findings indicate that the Pediatric Case Definition
for ME/CFS can distinguish between those with this
illness and controls, and between those with Severe
versus Moderate manifestations of the illness.

PMID: 19513826 [PubMed - indexed for MEDLINE]


Publication Types, MeSH Terms, Grant Support


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