your regime as interactions with drugs etc are possible.
Clin Biochem. 2012 Feb 10. [Epub ahead of print]
Coenzyme Q(10) in salivary cells correlate with blood cells in
Fibromyalgia: Improvement in clinical and biochemical parameter after
oral treatment.
Cordero MD, Santos-Garc=EDa R, Bermejo-Jover D, S=E1nchez-Dom=EDnguez B,
Jaramillo-Santos MR, Bull=F3n P.
Centro Andaluz de Biolog=EDa del Desarrollo (CABD), Universidad Pablo de
Olavide-CSIC-Junta de Andaluc=EDa, ISCIII, Sevilla, Spain; Centro de
Investigaci=F3n Biom=E9dica en Red de Enfermedades Raras (CIBERER),
ISCIII, Sevilla, Spain; Dpto. Citolog=EDa e Histolog=EDa Normal y
Patol=F3gica, Facultad de Medicina, Universidad de Sevilla, 41009
Sevilla, Spain.
Abstract
OBJECTIVE:
We have determined Coenzyme Q(10) (CoQ(10)) levels in salivary cells
(SCs) and mononuclear blood cells (BMCs) from Fibromyalgia (FM), and
we study the influence of oral CoQ(10) supplementation on cells levels
and clinical symptoms.
METHODS:
CoQ(10) was determined by high-performance liquid chromatography
(HPLC). Ten patients were supplemented daily with 300mg of CoQ(10)
during 3months.
RESULTS:
CoQ(10) were reduced in both cell models. Oral supplementation showed
an improvement in clinical symptoms and restored levels.
CONCLUSIONS:
Patients with FM showed an important dysfunction in CoQ(10) levels and
might benefit from oral supplementation.
Copyright =C2=A9 2012. Published by Elsevier Inc.
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