Expression of Lymphocyte Subsets and CD25~+ Regulative T Cells in
Peripheral Blood of Patients with Chronic Fatigue Syndrome
Labeled Immunoassays and Clinical Medicine=A1=B7 2011-02
LIU Ding-hua,LIU Zhan-dong,LI Yong-zhe,ZHANG Hai-ying,HU Chao-jun,
ZHANG Yong-bo,WHANG De-xin
(Department of Clinical Laboratory,Peking Union Medical College
Hospital,Chinese Academy of Medical Sciences and Peking Union Medical
College,Beijing 100730,China)
To investigate the expression of lymphocyte subsets and CD25+
regulative T cells in peripheral blood of patients with chronic
fatigue syndrome(CFS).
Eighty-four CFS patients and fifty healthy volunteers were enrolled in
this study.
Their peripheral blood was sampled,and the lymphocyte subsets and
CD25+ regulative T cells were measured by flow cytometry.
The results showed that the NK cells,CD4+T cells and CD25+ regulative
T cells in CFS patients were higher and B cells were lower than that
of healthy controls(P0.05),while there was no significant difference
between CFS patients and healthy controls with respect to the
percentage of T cells and CD8+T cells and CD4+/CD8+ ratio(P0.05).
The results indicated that CD25+ regulative T cell might play an
important role in CFS-related immunological abnormality,and be
involved in the progress of CFS.
=A1=BEKey Words=A1=BF=A3=BA Chronic fatigue syndrome Lymphocyte Regulative =
T cell
Flow cytometry
=A1=BEFund=A1=BF=A3=BA =B9=FA=BC=D2=B8=DF=BC=BC=CA=F5=D1=D0=BE=BF=B7=A2=D5=
=B9=BC=BC=BB=AE(863=BC=C6=BB=AE)=BB=F9=BD=F0=D7=CA=D6=FA=CF=EE=C4=BF(2006AA=
02Z436)
=A1=BECateGory Index=A1=BF=A3=BA R446.6
=A1=BEDOI=A1=BF=A3=BA CNKI:SUN:BJMY.0.2011-02-012
(I gave each sentence it's own paragraph)
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