[Article in Japanese]
Journal: Nippon Rinsho. 2009 Sep;67(9):1661-8
Author: Nakao M.
Affiliation: Department of Hygiene and Public Health & Division of
Psychosomatic Medicine, Teikyo University School of Medicine.
NLM Citation: PMID: 19768898
Functional somatic syndromes are defined as several related syndromes
that are characterized more by symptoms, suffering, and disability
than by structural or functional abnormality. These syndromes include
irritable bowel syndrome, tension-type headache, chronic fatigue
syndrome, and fibromyalgia. Such syndromes have similarities in terms
of definition, diagnosis, etiology, and treatment.
To elucidate the pathogenesis of functional somatic syndromes, it is
important to focus on gender-related factors, comorbidities of
depression and anxiety, physiological responses like autonomic
nervous function and hypothalamic-pituitary-adrenal axis, and
patient-doctor relationship.
Based on recent literatures, mood state and somatosensory
amplification are suggested to play an important role in the
psychopathological mechanism of functional somatic syndromes, and
genetic and environmental factors need to be considered as well.
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