Infectious mononucleosis-like syndrome probably attributable to
Coxsackie A virus infection
Burke A. Cunha, Nardeen Mickail, Andrew P. Petelin,
Heart & Lung: The Journal of Acute and Critical Care, Available online
30 January 2012, ISSN 0147-9563, 10.1016/j.hrtlng.2012.01.001.
Infectious mononucleosis (IM) is a clinical syndrome most often
attributable to Epstein-Barr virus (EBV). Characteristic clinical
features of EBV IM include bilateral upper lid edema, exudative or
nonexudative pharyngitis, bilateral posterior cervical adenopathy, and
splenomegaly =B1 maculopapular rash. Laboratory features of EBV IM
include atypical lymphocytes and elevated levels of serum
transaminases. Leukopenia and thrombocytopenia are not uncommon. The
syndrome of IM may also be attributable to other infectious diseases,
eg, cytomegalovirus (CMV), human herpes virus-6 (HHV-6), or Toxoplasma
gondii. Less commonly, viral hepatitis, leptospirosis, brucellosis, or
parvovirus B19 may present as an IM-like infection. To the best of our
knowledge, only 2 cases of IM-like infections attributable to
Coxsackie B viruses (B3 and B4) have been reported. We present the
first reported case of an IM-like syndrome with sore throat, fatigue,
atypical lymphocytes, and elevated levels of serum transaminases
likely due to Coxsackie A in an immunocompetent adult.
Keywords: Infectious mononucleosis; Coxsackie A virus; Mono-like
illness; Infectious mononucleosis syndrome; Atypical lymphocytes
http://www.sciencedirect.com/science/article/pii/S0147956312000027
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