below]
http://www.biomedcentral.com/1741-7015/3/19/comments#372644
Source of threshold for Symptom Inventory (SI) criteria
Tom Kindlon (20 November 2009) Irish ME/CFS Association - for
Information, Support & Research
This new set of criteria uses three sets of questionnaires: the SF-36, the
MFI and the Symptom Inventory (SI).
In the paper, we are given information on where the thresholds came from for
the first two instruments, but not the third one:
"We defined substantial reduction in occupational, educational, social, or
recreational activities as scores lower than the 25th percentile of
published US population [11] on the physical function (<= 70), or role
physical (<= 50), or social function (<= 75), or role emotional (<= 66.7)
subscales of the SF-36. We defined severe fatigue as >= medians of the MFI
general fatigue (>= 13) or reduced activity (>= 10) scales. Finally,
subjects reporting >=4 symptoms and scoring >= 25 on the Symptom Inventory
Case Definition Subscale were considered to have substantial accompanying
symptoms."
At the Chronic Fatigue Syndrome Advisory Committee (CFSAC) meeting [1], Dr
Bill Reeves gives the source of the threshold for the third criteria: "And
then we used the symptom inventory-a CFS individual had to have at least
four symptoms in addition to fatigue, and to have a score above the 10th
percentile of the nonfatigued group."
References:
[1] Chronic Fatigue Syndrome Advisory Committee (CFSAC) Meeting Monday,
April 24, 2006.
http://www.hhs.gov/advcomcfs/meetings/minutes/cfsac060424_min.html
Competing interests
No competing interests
=======
In case the paragraph starting, "We defined ...", does not come out
correctly:
"We defined substantial reduction in occupational, educational, social, or
recreational activities as scores lower than the 25th percentile of
published US population [11] on the physical function (less than or equal to
70), or role physical (less than or equal to 50), or social function (less
than or equal to 75), or role emotional (less than or equal to 66.7)
subscales of the SF-36. We defined severe fatigue as >= medians of the MFI
general fatigue (greater than or equal to 13) or reduced activity (greater
than or equal to 10) scales. Finally, subjects reporting greater than or
equal to 4 symptoms and scoring greater than or equal to 25 on the Symptom
Inventory Case Definition Subscale were considered to have substantial
accompanying symptoms."
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