ME and CFS was used.
Pediatr Int. 2011 Nov 24. doi: 10.1111/j.1442-200X.2011.03514.x. [Epub
ahead of print]
Fibromyalgia And Chronic Fatigue Syndrome In Children.
Itoh Y, Shigemori T, Igarashi T, Fukunaga Y.
Department of Pediatrics, Nippon Medical School, Tokyo, Japan.
Abstract
Objectives:=E2=80=82 Fibromyalgia (FM) is characterized by widespread
persistent pain and the presence of multiple discrete tender points.
Chronic fatigue syndrome (CFS) is a syndrome characterized by
debilitating fatigue associated with a variable number of nonspecific
complaints.
Since neither conditions had necessarily been recognized in children
until recently, those patients have been treated as school refusal
without being diagnosed as having either syndrome. There is a
considerable overlap of clinical symptoms between these two syndromes.
And so, it is controversy whether these syndromes are in the same
pathogenesis or not.
The objective in this article is to clarify the relationship between
these syndromes in children.
Methods:=E2=80=82 Fifteen patients with FM and twenty-one patients with CFS
were investigated both clinically and immunologically.
Immunological assessments included thorough analysis of autoantibodies
using several techniques.
Results:=E2=80=82 ANA titers were higher and the prevalence of anti-Sa was =
far
more frequent in CFS patients than in FM cases.
Conclusions:=E2=80=82 CFS and FM are diff erent from each other at least in
childhood from the immunological aspects, although a few patients were
suffering from both conditions.
=C2=A9 2011 The Authors. Pediatrics International =C2=A9 2011 Japan Pediatr=
ic Society.
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